What kind of mileage are you logging on your hex/cam R1200 bike before replacing it for long distance riding?
I'm about to roll 150k on my 2012 GSA, and I just LOVE the bike. But... it might be long in the tooth for something like a big rally in 2023, for example
I've always been taught that regular, routine maintenance is essential to a machine's longetivity. I don't mean "Run it until something breaks, and then replace the broken thing", I mean "routinely check wear items and repair/replace before failure".
I come from the trucking industry, where we run vehicles nearly every day and
expect engines to go 1 million miles before a major rebuild, using nothing more than routine and
scheduled maintenance (I think that last part is especially important). I know trucks aren't motorcycles (and as such, aren't really an apples-to-apples comparison), but the basic principle is sound - schedule your maintenance, follow it religiously, take care of growing problems before a catastrophic failure, and you'll be surprised how long things will last.
If you've taken care of your GSA throughout its life and it's working well for you, I don't see why you can't ride it for 250K or more. (That said, I'm really interested to know what your experience has been with maintenance issues with that bike, and if you've had rear drive issues.)