Is this part of a bigger trip, or are you just lining it up as a first 1600? If it was my first 1600, I'm not sure I'd go for this route. The only time I've ridden Melb-Adl-'Gutter on the clock I found it frustratingly difficult to hold a good moving average and, depending on your choice of route through SA, you really need to be in the ball with directions and turns... which of course leads to documentation challenges.
This is before you get to other things like wildlife and remote areas. All things are solvable, but if it is your first attempt at an iba length run, you may not want to fork out several hundred dollars to get lights that will make this route easier and safer.
Perhaps look at an out and back run or design a simple loop which puts you on the Hume during the worst hours (dawn/dusk)
Just my 2 bobs worth and, of course if you were already heading towards the NT anyway, feel free to ignore all of the above and enjoy the ride!